Death Stranding launches with a lot to talk about, and a plot and setting many find complicated. You spend a lot of time listening to people talk in this game, and thankfully the actors each give quite good performances for their characters. This is especially impressive given that most of the cast are not professional voice actors, being more at home directly on the screen (with Troy Baker as the only notable exception among the important characters). Live actors tend to be hit or miss when taking on voice acting projects, but everyone here hits it out of the park.
Sam Porter Bridges is voiced by Norman Reedus, probably best known for his role as Darryl on The Walking Dead.
Clifford Unger is brought to life by Mads Mikkelsen, of Hannibal fame.
Fragile is voiced by Léa Seydoux, known for films like The Grand Budapest Hotel and Spectre.
Higgs comes to us by way of Troy Baker, with almost too many voice roles to mention. Most will at least know him as Joel form The Last of Us.
Locene is voiced by Margaret Qualley, of films like Once Upon A Time In Hollywood.
Die-Hardman is given a voice by Tommie Earl Jenkins, who was in several episodes of Pandora.
Deadman is voiced by Jesse Corti, veteran voice actor perhaps still best known as LeFou from Disney’s Beauty and the Beast.
Heartman is voiced by Darren Jacobs, of Suspense.
Bridget is performed by Lindsay Wagner, who among many other things was The Bionic Woman.
The Wandering MC makes a brief appearance, voiced by Conan O’Brien.
There are a few other voice actors doing additional voices for minor characters (such as Mathew Mercer as the Ludens Fan), but the main cast is fairly tight for this game, which probably helps explain why they’re all so well acted.