Destiny 2 has Lost Sectors hidden all over it. These locations have enemies everywhere, and if you kill them all and wipe out the Major at the end, you will get access to a cache that contains some loot. They can also tie into all sorts of other activities, like Bounties from Spider, Exotic Quests, and other missions that you will run into while you play the game.
Destiny 2 – Where To Find The Sanctum of Bones
The Sanctum of Bones is, thankfully, pretty easy to find. First, you need to head to Io and spawn at the point near Asher Mir. Once you get there, turn around and head between the outcropping of rocks towards the cliff face opposite.
You should be able to see a glowing red light in front of you, besides the symbol for the Lost Sector. Just make your way behind that group of stones, and you will find an entrance in the wall.
Head inside and down the tunnel and you will come to the entrance of the Sanctum of Bones. If you are here to hunt Pandrol, The Pillar of Nothing, you will need to venture into the back. Go up the ramp in the first cave and follow it the whole way around, through the tunnels and past the area with the Blights. Jump across the stone platform to the tunnel on the other side and keep going you will eventually come to where Pandrol likes to hang out. There are a lot of enemies in this Lost Sector, so if you are new to the game, it is best to go slowly. Just clear out the enemies as you make your way through the caves and tunnels.
And that’s it, as I said, not the hardest Lost Sector to find, as long as you know where to look — best of luck, Guardian.