Mewtwo is a powerful Pokémon in Pokémon Go. You can only obtain it through rare events. Typically, you have to battle it from a five-star raid, but some events in the mobile game give you the chance to encounter it after completing several research tasks. When you do receive this Pokémon, you want to optimize it to the best of your ability. It has several attacks available to it, but there are a few clear choices you wish to use, and others you want to steer away from having on yours.
Mewtwo is purely a Psychic-type. It has the maximum CP of 4,178, an attack of 300, a defense of 182, and a stamina of 214. It’s a powerhouse when it comes to damage, but it does lack in defense, so if you find yourself facing a Bug, Dark, or Ghost-type Pokémon, you’re better off attempting to switch it out for an alternative choice. But it’s great to use in PvE raids against Pokémon types that Mewtwo can land super-effective attacks against, such as Fighting and Poison-types.
These are all of the moves Mewtwo can learn:
- Psycho cut (Psychic-type) (6 Damage, and 8 Energy)
- Confusion (Psychic-type) (24 Damage, and 15 Energy)
- Flamethrower (Fire-type)
- Focus blast (Fighting-type)
- Hyper beam (Normal-type)
- Ice beam (Ice-type)
- Psychic (Psychic-Type)
- Psystrike (Psychic-type)
- Shadowball (Ghost-type)
- Thunderbolt (Electric-type)
Mewtwo has several options to pick from, and it’s sometimes difficult to choose between them. Of the two fast moves, you want to lean more towards confusion because it does the most damage to your opponent. Confusion has a higher output of damage compared to psycho cut, so you primarily want to focus on that one being Mewtwo’s primary attack, given a choice between them. For your charge move, you have a bit more variety, but there are some distinctly superior options.
Of the moves available, you want a Mewtwo that knows psystrike or shadow ball. Unfortunately, these are Legacy moves, which mean you can only receive them from Mewtwo you captured during limited-time event. However, if you have an Elite Charged TM from the battle league, you can choose any of the above choices. Psystrike is your best bet, but Shadowball is also at the top of the list. Those are two primary choices for the best Mewtwo, and any other Mewtwo you have can fill a useful role in a roster based on their charge move, or you can focus on those two. Because of how difficult it can be to receive an Elite TM, you probably want to have one that knows psychic, focus blast, or flamethrower.
Outside of a few rare occasions, you won’t have too many chances to capture Mewtwo, so when you do, consider the choices available to you. If you only have one Mewtwo, it’s better to focus on confusion with psystrike or shadow ball.